Mouse Fgd4 activation kit by CRISPRa

SKU
GA213660
Fgd4 CRISPRa kit - CRISPR gene activation of mouse FYVE, RhoGEF and PH domain containing 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fgd4
Locus ID 224014
Components

GA213660G1, Fgd4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213660G2, Fgd4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213660G3, Fgd4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001301817, NM_001301818, NM_139232, NM_139233, NM_139234
UniProt ID Q91ZT5
Synonyms 9030023J02Rik; 9330209B17Rik; Frabp; ZFYVE6
Summary This gene is a member of the FYVE, RhoGEF and PH domain containing (FGD) family. The encoded protein is a Cdc42-specific guanine nucleotide exchange factor (GEF) that plays an essential role in regulating the actin cytoskeleton and cell morphology. Disruption of the gene in mouse causes abnormal nerve development and dysmyelination. Mutations in a similar gene in human can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2014
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Documents
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Other Versions
SKU Description Size Price
KN505917 Fgd4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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