Mouse Brd1 activation kit by CRISPRa

SKU GA213640

Brd1 CRISPRa kit - CRISPR gene activation of mouse bromodomain containing 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Brd1
• Locus ID: 223770
• Components:

  GA213640G1, Brd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA213640G2, Brd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA213640G3, Brd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001033274
• Synonyms: 1110059H06Rik; AI316859; mKIAA4191
• Summary: Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, that acts as a regulator of hematopoiesis (PubMed:21753189). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby promoting erythroid differentiation (PubMed:21753189).[UniProtKB/Swiss-Prot Function]