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Mouse Il31ra activation kit by CRISPRa

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SKU
GA213557
Il31ra CRISPRa kit - CRISPR gene activation of mouse interleukin 31 receptor A
  $1,657.00
4 Weeks*

Other products for "Il31ra"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Il31ra
Locus ID 218624
Components

GA213557G1, Il31ra gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213557G2, Il31ra gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213557G3, Il31ra gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_139299
UniProt ID Q8K5B1
Synonyms CRL3; GLM-R; Glmr; GPL; NR10
Summary Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (PubMed:24373353). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (PubMed:17379091).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN508284 Il31ra - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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