Mouse Nrde2 activation kit by CRISPRa

SKU
GA213505
Nrde2 CRISPRa kit - CRISPR gene activation of mouse nrde-2 necessary for RNA interference, domain containing
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Nrde2
Locus ID 217827
Components

GA213505G1, Nrde2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213505G2, Nrde2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213505G3, Nrde2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001290303, NM_183155
UniProt ID Q80XC6
Synonyms 6720454P05Rik
Summary Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing various RNAs to exosomal degradation. Changes the conformation of MTREX, precluding its association with the nuclear exosome and interaction with proteins required for its function in RNA exosomal degradation. Negatively regulates, for instance, the degradation of mRNAs and lncRNAs by inhibiting their MTREX-mediated recruitment to nuclear exosome. By preventing the degradation of RNAs in the nucleus, it promotes their export to the cytoplasm.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN511226 Nrde2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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