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Mouse Cipc activation kit by CRISPRa

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SKU
GA213498
Cipc CRISPRa kit - CRISPR gene activation of mouse CLOCK interacting protein, circadian
  $1,657.00
4 Weeks*

Other products for "Cipc"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cipc
Locus ID 217732
Components

GA213498G1, Cipc gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213498G2, Cipc gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213498G3, Cipc gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001289429, NM_001289430, NM_001289431, NM_001289432, NM_173735, NR_033623, NM_001364274
UniProt ID Q8R0W1
Synonyms 2310044G17Rik; AI842544; AI853744; Kiaa1737; mKIAA1737
Summary Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK (PubMed:17310242, PubMed:19414601). However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock (PubMed:25862660).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN503355 Cipc - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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