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Mouse Ccm2 activation kit by CRISPRa

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SKU
GA213359
Ccm2 CRISPRa kit - CRISPR gene activation of mouse cerebral cavernous malformation 2
  $1,657.00
4 Weeks*

Other products for "Ccm2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ccm2
Locus ID 216527
Components

GA213359G1, Ccm2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213359G2, Ccm2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213359G3, Ccm2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001190343, NM_001190344, NM_146014
UniProt ID Q8K2Y9
Synonyms BC029157
Summary Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May also function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN502800 Ccm2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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