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Mouse Socs2 activation kit by CRISPRa

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SKU
GA213337
Socs2 CRISPRa kit - CRISPR gene activation of mouse suppressor of cytokine signaling 2
  $1,657.00
4 Weeks*

Other products for "Socs2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Socs2
Locus ID 216233
Components

GA213337G1, Socs2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213337G2, Socs2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213337G3, Socs2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001168655, NM_001168656, NM_001168657, NM_007706
UniProt ID O35717
Synonyms 8030460M17; AI527257; AW108012; CIS2; Cish2; D130043N08Rik; hg; JAB; SOCS-2; SSI-2
Summary SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN516455 Socs2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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