Mouse Rap1b activation kit by CRISPRa

SKU GA213280

Rap1b CRISPRa kit - CRISPR gene activation of mouse RAS related protein 1b

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Rap1b
• Locus ID: 215449
• Components:

  GA213280G1, Rap1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA213280G2, Rap1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA213280G3, Rap1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024457
• UniProt ID: Q99JI6
• Synonyms: 2810443E11Rik
• Summary: GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity).[UniProtKB/Swiss-Prot Function]