Mouse Astl activation kit by CRISPRa

SKU
GA213260
Astl CRISPRa kit - CRISPR gene activation of mouse astacin-like metalloendopeptidase (M12 family)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Astl
Locus ID 215095
Components

GA213260G1, Astl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213260G2, Astl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213260G3, Astl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001291003, NM_172539
UniProt ID Q6HA09
Synonyms 7420700F21; C87576; Sas1b
Summary Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN501700 Astl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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