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Mouse Plekhg6 activation kit by CRISPRa

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SKU
GA213161
Plekhg6 CRISPRa kit - CRISPR gene activation of mouse pleckstrin homology domain containing, family G (with RhoGef domain) member 6
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Plekhg6
Locus ID 213522
Components

GA213161G1, Plekhg6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213161G2, Plekhg6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213161G3, Plekhg6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_198604
UniProt ID Q8R0J1
Synonyms BC026778; Gm155
Summary Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN513456 Plekhg6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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