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Mouse Fancd2 activation kit by CRISPRa

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SKU
GA213043
Fancd2 CRISPRa kit - CRISPR gene activation of mouse Fanconi anemia, complementation group D2
  $1,657.00
4 Weeks*

Other products for "Fancd2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Fancd2
Locus ID 211651
Components

GA213043G1, Fancd2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213043G2, Fancd2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213043G3, Fancd2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001033244, NM_001347350
UniProt ID Q80V62
Synonyms 2410150O07Rik; AU015151; BB137857; FA-D2; FA4; FACD; FAD; FANCD
Summary Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress (By similarity). Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN505744 Fancd2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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