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Mouse Dock10 activation kit by CRISPRa

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SKU
GA212975
Dock10 CRISPRa kit - CRISPR gene activation of mouse dedicator of cytokinesis 10
  $1,657.00
4 Weeks*

Other products for "Dock10"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Dock10
Locus ID 210293
Components

GA212975G1, Dock10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212975G2, Dock10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212975G3, Dock10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001285927, NM_175291
UniProt ID Q8BZN6
Synonyms 9330153B10Rik; A630054M16Rik; Jr4; Jr5; mKIAA0694; R75174; ZIZ3; Zizimin3
Summary Guanine nucleotide-exchange factor (GEF) that activates CDC42 and RAC1 by exchanging bound GDP for free GTP. Essential for dendritic spine morphogenesis in Purkinje cells and in hippocampal neurons, via a CDC42-mediated pathway (PubMed:25851601). Sustains B-cell lymphopoiesis in secondary lymphoid tissues and regulates FCER2/CD23 expression (PubMed:27502165).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN504735 Dock10 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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