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Mouse Mtrr activation kit by CRISPRa

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SKU
GA212956
Mtrr CRISPRa kit - CRISPR gene activation of mouse 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Mtrr
Locus ID 210009
Components

GA212956G1, Mtrr gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212956G2, Mtrr gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212956G3, Mtrr gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_172480, NR_131892
UniProt ID Q8C1A3
Synonyms 4732420G08; MSR
Summary Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Mutations in a similar gene in human have been associated with cblE complementation type homocystinuria-megaloblastic anemia and susceptibility to folate-sensitive neural tube defects. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, May 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN510509 Mtrr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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