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Mouse Trp53bp2 activation kit by CRISPRa

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SKU
GA212936
Trp53bp2 CRISPRa kit - CRISPR gene activation of mouse transformation related protein 53 binding protein 2
  $1,657.00
4 Weeks*

Other products for "Trp53bp2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Trp53bp2
Locus ID 209456
Components

GA212936G1, Trp53bp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212936G2, Trp53bp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212936G3, Trp53bp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_173378
UniProt ID Q8CG79
Synonyms 53BP2; AI746547; ASPP2; PPP1R13A; Tp53bp2; X98550
Summary Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates p53/TP53 by enhancing the DNA binding and transactivation function of p53/TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42 (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN518280 Trp53bp2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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