Mouse Ripk2 activation kit by CRISPRa

SKU GA212726

Ripk2 CRISPRa kit - CRISPR gene activation of mouse receptor (TNFRSF)-interacting serine-threonine kinase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Ripk2
• Locus ID: 192656
• Components:

  GA212726G1, Ripk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212726G2, Ripk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212726G3, Ripk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_138952, NR_138102
• UniProt ID: P58801
• Synonyms: 2210420D18Rik; CARD3; CARDIAK; CCK; D4Bwg0615e; RICK; RIP2
• Summary: This gene encodes a member of the receptor-interacting protein family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain, and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of nuclear factor kappa B and inducer of apoptosis in response to various stimuli. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]