Mouse Prpf8 activation kit by CRISPRa

SKU
GA212689
Prpf8 CRISPRa kit - CRISPR gene activation of mouse pre-mRNA processing factor 8
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Prpf8
Locus ID 192159
Components

GA212689G1, Prpf8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212689G2, Prpf8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212689G3, Prpf8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_138659
UniProt ID Q99PV0
Synonyms AU019467; D11Bwg0410e; DBF3/PRP8; Prp8; Sfprp8l
Summary Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN513977 Prpf8 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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