Mouse Capn8 activation kit by CRISPRa

SKU GA212576

Capn8 CRISPRa kit - CRISPR gene activation of mouse calpain 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Capn8
• Locus ID: 170725
• Components:

  GA212576G1, Capn8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA212576G2, Capn8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA212576G3, Capn8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001145806, NM_130890
• UniProt ID: Q91VA3
• Synonyms: nCL-2; nCL-2'
• Summary: Calcium-regulated non-lysosomal thiol-protease (By similarity). Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex.[UniProtKB/Swiss-Prot Function]