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Mouse Ttbk2 activation kit by CRISPRa

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SKU
GA212539
Ttbk2 CRISPRa kit - CRISPR gene activation of mouse tau tubulin kinase 2
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ttbk2
Locus ID 140810
Components

GA212539G1, Ttbk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212539G2, Ttbk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212539G3, Ttbk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001024856, NM_001024857, NM_080788
UniProt ID Q3UVR3
Synonyms 2610507N02Rik; AI326283; B930008N24Rik; mKIAA0847; Ttbk; Ttbk1; TTK
Summary Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN518391 Ttbk2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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