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Mouse Ivns1abp activation kit by CRISPRa

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SKU
GA212482
Ivns1abp CRISPRa kit - CRISPR gene activation of mouse influenza virus NS1A binding protein
  $1,657.00
4 Weeks*

Other products for "Ivns1abp"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ivns1abp
Locus ID 117198
Components

GA212482G1, Ivns1abp gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212482G2, Ivns1abp gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212482G3, Ivns1abp gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001039511, NM_001039512, NM_054102, NM_001359262, NM_001359263, NM_028582
UniProt ID Q920Q8
Synonyms 1190004M08Rik; 1700126I16Rik; AA960440; HSPC068; mKIAA0850; ND1; Nd1-L; Nd1-S; NS-1; NS1-BP
Summary Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (PubMed:12213805, PubMed:16317045). Protects cells from cell death induced by actin destabilization (PubMed:16952015). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription (By similarity). In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors (By similarity). Inhibits pre-mRNA splicing (in vitro) (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN508527 Ivns1abp - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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