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Mouse Selenom activation kit by CRISPRa

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SKU
GA212434
Selenom CRISPRa kit - CRISPR gene activation of mouse selenoprotein M
  $1,657.00
4 Weeks*

Other products for "Selenom"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Selenom
Locus ID 114679
Components

GA212434G1, Selenom gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212434G2, Selenom gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212434G3, Selenom gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_053267
UniProt ID Q8VHC3
Synonyms 1500040L08Rik; A230103K18; Selm; Sepm
Summary The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. provided by RefSeq, Dec 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN515488 Selm - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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