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Mouse Ovol2 activation kit by CRISPRa

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SKU
GA212016
Ovol2 CRISPRa kit - CRISPR gene activation of mouse ovo like zinc finger 2
  $1,657.00
4 Weeks*

Other products for "Ovol2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ovol2
Locus ID 107586
Components

GA212016G1, Ovol2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212016G2, Ovol2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212016G3, Ovol2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_026924, NM_152947
UniProt ID Q8CIV7
Synonyms 1700108N11Rik; 1810007D21Rik; M-OVO; M-OVO-A; M-OVO-B; MOVO; movo2; Ovo2; Zfp339
Summary Zinc-finger transcription repressor factor (PubMed:15225875, PubMed:23319585). Plays a critical role in maintaining the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition (EMT) mainly through the repression of ZEB1, an EMT inducer (PubMed:24735878, PubMed:24735879). Positively regulates neuronal differentiation (PubMed:16423343, PubMed:23319585). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1 (By similarity). Important for the correct development of primordial germ cells in embryos (PubMed:28059165).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN512695 Ovol2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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