Mouse Slf1 activation kit by CRISPRa

SKU
GA211866
Slf1 CRISPRa kit - CRISPR gene activation of mouse SMC5-SMC6 complex localization factor 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Slf1
Locus ID 105377
Components

GA211866G1, Slf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211866G2, Slf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211866G3, Slf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_134071
UniProt ID Q8R3P9
Synonyms 2700017A04Rik; Ankrd32; AW545819; Brctd1; Brctx; C730024G01Rik
Summary Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks. Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN501280 Ankrd32 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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