Mouse Inca1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Inca1 |
| Locus ID | 103844 |
| Components |
GA211768G1, Inca1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211768G2, Inca1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211768G3, Inca1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001252482, NM_001252483, NM_001252484, NM_001252485, NM_213729 |
| UniProt ID | Q6PKN7 |
| Synonyms | AI842396 |
| Summary | Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and proliferation and may play a role in cell cycle control (PubMed:21540187). Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth (PubMed:21750715).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN508323 | Inca1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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