Mouse Ccp110 activation kit by CRISPRa

SKU
GA211657
Ccp110 CRISPRa kit - CRISPR gene activation of mouse centriolar coiled coil protein 110
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ccp110
Locus ID 101565
Components

GA211657G1, Ccp110 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211657G2, Ccp110 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211657G3, Ccp110 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_182995, NM_001360793, NM_001360794
UniProt ID Q7TSH4
Synonyms 6330503K22Rik; AA415922; AI427129; AW557948; CP110
Summary Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:23141541). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (PubMed:26965371). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN502830 Ccp110 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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