Mouse Pds5b activation kit by CRISPRa

SKU GA211616

Pds5b CRISPRa kit - CRISPR gene activation of mouse PDS5 cohesin associated factor B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Pds5b
• Locus ID: 100710
• Components:

  GA211616G1, Pds5b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211616G2, Pds5b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211616G3, Pds5b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001346503, NM_175310
• UniProt ID: Q4VA53
• Synonyms: AI646570; Aprin; AS3; AW212954; mKIAA0979; Tg(Wap-ERBB2)229Wzw; WAP-Her-2
• Summary: Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells (By similarity).[UniProtKB/Swiss-Prot Function]