Mouse Ppp1r8 activation kit by CRISPRa

SKU GA211596

Ppp1r8 CRISPRa kit - CRISPR gene activation of mouse protein phosphatase 1, regulatory subunit 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Ppp1r8
• Locus ID: 100336
• Components:

  GA211596G1, Ppp1r8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211596G2, Ppp1r8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211596G3, Ppp1r8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001290725, NM_146154, NM_001355198, NM_001355199
• UniProt ID: Q8R3G1
• Synonyms: 6330548N22Rik; AU044684; NIPP1
• Summary: Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Essential for cell proliferation and early embryonic development.[UniProtKB/Swiss-Prot Function]