Mouse Lrrc59 activation kit by CRISPRa

SKU GA211495

Lrrc59 CRISPRa kit - CRISPR gene activation of mouse leucine rich repeat containing 59

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Lrrc59
• Locus ID: 98238
• Components:

  GA211495G1, Lrrc59 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211495G2, Lrrc59 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211495G3, Lrrc59 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_133807
• UniProt ID: Q922Q8
• Synonyms: AA959742; C78668
• Summary: Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores (By similarity).[UniProtKB/Swiss-Prot Function]