Mouse Cpsf1 activation kit by CRISPRa

SKU GA211440

Cpsf1 CRISPRa kit - CRISPR gene activation of mouse cleavage and polyadenylation specific factor 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Cpsf1
• Locus ID: 94230
• Components:

  GA211440G1, Cpsf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211440G2, Cpsf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211440G3, Cpsf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001164173, NM_053193, NM_001361485
• UniProt ID: Q9EPU4
• Summary: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).[UniProtKB/Swiss-Prot Function]