Mouse Pag1 activation kit by CRISPRa

SKU
GA211425
Pag1 CRISPRa kit - CRISPR gene activation of mouse phosphoprotein associated with glycosphingolipid microdomains 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pag1
Locus ID 94212
Components

GA211425G1, Pag1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211425G2, Pag1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211425G3, Pag1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001195031, NM_053182
UniProt ID Q3U1F9
Synonyms Cbp; F730007C19Rik; Pag
Summary Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN512755 Pag1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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