Mouse Vangl2 activation kit by CRISPRa

SKU
GA211362
Vangl2 CRISPRa kit - CRISPR gene activation of mouse VANGL planar cell polarity 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vangl2
Locus ID 93840
Components

GA211362G1, Vangl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211362G2, Vangl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211362G3, Vangl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_033509
UniProt ID Q91ZD4
Synonyms C530001F03Rik; loop-tail; Lootl; Lp; Lpp1; Ltap; ska17; ska; stbm; strabismus; Vang1l2
Summary Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (PubMed:16495441).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN518850 Vangl2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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