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Mouse Gabarapl2 activation kit by CRISPRa

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SKU
GA211347
Gabarapl2 CRISPRa kit - CRISPR gene activation of mouse gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
  $1,657.00
4 Weeks*

Other products for "Gabarapl2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Gabarapl2
Locus ID 93739
Components

GA211347G1, Gabarapl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211347G2, Gabarapl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211347G3, Gabarapl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_026693
UniProt ID P60521
Synonyms 0610012F20Rik; 2900019O08Rik; AI173605; GATE-16; Gef2
Summary Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN506230 Gabarapl2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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