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Mouse Il23a activation kit by CRISPRa

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SKU
GA211218
Il23a CRISPRa kit - CRISPR gene activation of mouse interleukin 23, alpha subunit p19
  $1,657.00
4 Weeks*

Other products for "Il23a"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Il23a
Locus ID 83430
Components

GA211218G1, Il23a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211218G2, Il23a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211218G3, Il23a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_031252
UniProt ID Q9EQ14
Synonyms IL-23; p19
Summary Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN508273 Il23a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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