Mouse Lias activation kit by CRISPRa

SKU GA211099

Lias CRISPRa kit - CRISPR gene activation of mouse lipoic acid synthetase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Lias
• Locus ID: 79464
• Components:

  GA211099G1, Lias gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA211099G2, Lias gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA211099G3, Lias gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001310612, NM_024471
• UniProt ID: Q99M04
• Synonyms: 7a5ex; 2900022L22Rik; 4933425M12Rik; C77512; lip-syn; LS
• Summary: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.[UniProtKB/Swiss-Prot Function]