Mouse Lsm6 activation kit by CRISPRa

SKU
GA211003
Lsm6 CRISPRa kit - CRISPR gene activation of mouse LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Lsm6
Locus ID 78651
Components

GA211003G1, Lsm6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211003G2, Lsm6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211003G3, Lsm6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001191004, NM_030145
UniProt ID P62313
Synonyms 1500031N17Rik; 2410088K19Rik; AI747288
Summary Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN509536 Lsm6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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