Mouse Mccc2 activation kit by CRISPRa

SKU GA210868

Mccc2 CRISPRa kit - CRISPR gene activation of mouse methylcrotonoyl-Coenzyme A carboxylase 2 (beta)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Mccc2
• Locus ID: 78038
• Components:

  GA210868G1, Mccc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210868G2, Mccc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210868G3, Mccc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_030026
• UniProt ID: Q3ULD5
• Synonyms: 4930552N12Rik; MCCB
• Summary: Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.[UniProtKB/Swiss-Prot Function]