Mouse Rnf170 activation kit by CRISPRa

SKU GA210812

Rnf170 CRISPRa kit - CRISPR gene activation of mouse ring finger protein 170

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Rnf170
• Locus ID: 77733
• Components:

  GA210812G1, Rnf170 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210812G2, Rnf170 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210812G3, Rnf170 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_029965, NM_001357292, NM_001357293, NM_001357294, NM_001357295, NR_151666, NR_151667
• UniProt ID: Q8CBG9
• Synonyms: 6720407G21Rik; AI481227
• Summary: E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.[UniProtKB/Swiss-Prot Function]