Mouse Mrap activation kit by CRISPRa

SKU GA210691

Mrap CRISPRa kit - CRISPR gene activation of mouse melanocortin 2 receptor accessory protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Mrap
• Locus ID: 77037
• Components:

  GA210691G1, Mrap gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210691G2, Mrap gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210691G3, Mrap gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_029844
• UniProt ID: Q9D159
• Synonyms: 1110025G12Rik; C21ORF61; Falp; ORF61
• Summary: Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells (By similarity).[UniProtKB/Swiss-Prot Function]