Mouse Upp2 activation kit by CRISPRa

SKU GA210573

Upp2 CRISPRa kit - CRISPR gene activation of mouse uridine phosphorylase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Upp2
• Locus ID: 76654
• Components:

  GA210573G1, Upp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA210573G2, Upp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA210573G3, Upp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001289659, NM_001289660, NM_029692
• UniProt ID: Q8CGR7
• Synonyms: 1700124F02Rik; AI266885; UDRPASE2; UP2; UPASE2
• Summary: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).[UniProtKB/Swiss-Prot Function]