Mouse Ppp1r11 activation kit by CRISPRa

SKU
GA210527
Ppp1r11 CRISPRa kit - CRISPR gene activation of mouse protein phosphatase 1, regulatory inhibitor subunit 11
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ppp1r11
Locus ID 76497
Components

GA210527G1, Ppp1r11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA210527G2, Ppp1r11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA210527G3, Ppp1r11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_029632
UniProt ID Q8K1L5
Synonyms 1500041B02Rik; AV117883; Hcgv; Tcte5; Tctex-5; Tctex5
Summary Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN513726 Ppp1r11 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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