Mouse Meiob activation kit by CRISPRa

SKU
GA210123
Meiob CRISPRa kit - CRISPR gene activation of mouse meiosis specific with OB domains
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Meiob
Locus ID 75178
Components

GA210123G1, Meiob gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA210123G2, Meiob gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA210123G3, Meiob gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_029197
UniProt ID Q9D513
Synonyms 4930528F23Rik; MLZ-675
Summary Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN509964 Meiob - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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