Mouse Zfp263 activation kit by CRISPRa

SKU GA209726

Zfp263 CRISPRa kit - CRISPR gene activation of mouse zinc finger protein 263

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Zfp263
• Locus ID: 74120
• Components:

  GA209726G1, Zfp263 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA209726G2, Zfp263 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA209726G3, Zfp263 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_148924
• UniProt ID: Q8CF60
• Synonyms: 1200014J04Rik; AI326880; AU020888; mFPM315; NT2
• Summary: Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor (By similarity). Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression (By similarity). Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions (By similarity).[UniProtKB/Swiss-Prot Function]