Mouse Thoc3 activation kit by CRISPRa

SKU
GA209569
Thoc3 CRISPRa kit - CRISPR gene activation of mouse THO complex 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Thoc3
Locus ID 73666
Components

GA209569G1, Thoc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209569G2, Thoc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209569G3, Thoc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_028597
UniProt ID Q8VE80
Synonyms 2410044K02Rik; AL033344
Summary Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN517533 Thoc3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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