Mouse Marchf1 activation kit by CRISPRa

SKU
GA209365
March1 CRISPRa kit - CRISPR gene activation of mouse membrane-associated ring finger (C3HC4) 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Marchf1
Locus ID 72925
Components

GA209365G1, Marchf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209365G2, Marchf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209365G3, Marchf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001166372, NM_001166375, NM_001293784, NM_175188, NM_001363123, NM_001363124, NM_001363125
UniProt ID Q6NZQ8
Synonyms 2900024D24Rik; BB085186
Summary E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN509782 March1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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