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Mouse Ndufv2 activation kit by CRISPRa

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SKU
GA209363
Ndufv2 CRISPRa kit - CRISPR gene activation of mouse NADH:ubiquinone oxidoreductase core subunit V2
  $1,657.00
4 Weeks*

Other products for "Ndufv2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ndufv2
Locus ID 72900
Components

GA209363G1, Ndufv2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209363G2, Ndufv2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209363G3, Ndufv2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001278415, NM_028388
UniProt ID Q9D6J6
Synonyms 2900010C23Rik
Summary This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyzes the transfer of electrons from NADH to the electron acceptor ubiquinone. The proton gradient created by electron transfer drives the conversion of ADP to ATP. This gene is a core subunit and is conserved in prokaryotes and eukaryotes. The bovine ortholog of this protein has been characterized and is reported to contain an iron-sulfur cluster, which may be involved in electron transfer. In humans mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jun 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN510863 Ndufv2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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