Mouse Ubash3b activation kit by CRISPRa

SKU
GA209350
Ubash3b CRISPRa kit - CRISPR gene activation of mouse ubiquitin associated and SH3 domain containing, B
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ubash3b
Locus ID 72828
Components

GA209350G1, Ubash3b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209350G2, Ubash3b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209350G3, Ubash3b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_176860, NM_001357412
UniProt ID Q8BGG7
Synonyms 2810457I06Rik; BB125008; p70; TULA-2
Summary Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN518558 Ubash3b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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