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Mouse Selenoh activation kit by CRISPRa

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SKU
GA209304
Selenoh CRISPRa kit - CRISPR gene activation of mouse selenoprotein H
  $1,657.00
4 Weeks*

Other products for "Selenoh"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Selenoh
Locus ID 72657
Components

GA209304G1, Selenoh gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209304G2, Selenoh gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209304G3, Selenoh gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001033166, NM_001037279
UniProt ID Q3UQA7
Synonyms 2700094K13Rik; Selh
Summary This gene encodes a nucleolar protein, which belongs to the SelWTH family. It functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, May 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN500291 2700094K13Rik - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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