Mouse Zup1 activation kit by CRISPRa

SKU GA209282

Zup1 CRISPRa kit - CRISPR gene activation of mouse zinc finger containing ubiquitin peptidase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Zup1
• Locus ID: 72580
• Components:

  GA209282G1, Zup1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA209282G2, Zup1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA209282G3, Zup1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_028287, NM_001359455, NM_001359456, NR_153113
• UniProt ID: Q3T9Z9
• Synonyms: 2700019D07Rik
• Summary: Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.[UniProtKB/Swiss-Prot Function]