Mouse Prr5l activation kit by CRISPRa

SKU
GA209239
Prr5l CRISPRa kit - CRISPR gene activation of mouse proline rich 5 like
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Prr5l
Locus ID 72446
Components

GA209239G1, Prr5l gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209239G2, Prr5l gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209239G3, Prr5l gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001083810, NM_001110849, NM_175181, NM_001355625
UniProt ID A2AVJ5
Synonyms 2600010E01Rik; 4833411O04Rik; Protor-2; Protor2
Summary Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton (By similarity). Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration (PubMed:22609986). Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress. Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN514003 Prr5l - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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