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Mouse Castor1 activation kit by CRISPRa

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SKU
GA209034
Castor1 CRISPRa kit - CRISPR gene activation of mouse cytosolic arginine sensor for mTORC1 subunit 1
  $1,657.00
4 Weeks*

Other products for "Castor1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Castor1
Locus ID 71962
Components

GA209034G1, Castor1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209034G2, Castor1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209034G3, Castor1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_028022
UniProt ID Q9CWQ8
Synonyms 2410008K03Rik
Summary Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN506333 Gatsl3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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