Mouse Coq2 activation kit by CRISPRa

SKU GA208994

Coq2 CRISPRa kit - CRISPR gene activation of mouse coenzyme Q2 4-hydroxybenzoate polyprenyltransferase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Coq2
• Locus ID: 71883
• Components:

  GA208994G1, Coq2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA208994G2, Coq2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA208994G3, Coq2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_027978
• UniProt ID: Q66JT7
• Synonyms: 2310002F18Rik; PHB:PPT
• Summary: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.[UniProtKB/Swiss-Prot Function]